پیراسیٹامول: گردانَن مَنٛز فَرَق

'''پیراسیٹامول'''، یتھیَتھ ا'''یسیٹامینوفین''' تہِ ونان چھِ، چھُ اکھاَکھ دوا یُس [[دَگ]] تہٕ [[تَپھ]] علاج کرنہٕ خٲطرٕ استعمالاِستِمال چھُ یِوان کرنہٕ۔<ref name="AHFS20162">{{cite web|title=Acetaminophen|url=https://www.drugs.com/monograph/acetaminophen.html|url-status=live|archive-url=https://web.archive.org/web/20160605063136/http://www.drugs.com/monograph/acetaminophen.html|archive-date=5 June 2016|access-date=16 September 2016|publisher=The American Society of Health-System Pharmacists}}</ref><ref name="pmid287349392">{{cite journal|last1=Lee|first1=WM|date=December 2017|title=Acetaminophen (APAP) hepatotoxicity-Isn't it time for APAP to go away?|journal=Journal of Hepatology|volume=67|issue=6|pages=1324–1331|doi=10.1016/j.jhep.2017.07.005|pmc=5696016|pmid=28734939}}</ref> یہِ چھُ عموٗمَن ہلکہٕ پؠٹھٕ درمیٲنی دَگہِ منٛزمَنٛز راحت باپتھ استعمالاِستِمال یِوان کرنہٕ۔<ref name="AHFS20162" /> کیٚنٛہہ ثبوٗتن ہُنٛد خیال چھُ زِ امہِ سٟتؠ چھِ تپھ وٲلؠ شُرؠ ٹھنڈ کرنس منٛزمَنٛز مدد مِلان، مگر باقٕے چھِنہٕ یوٗتاہ یقین تھاوان۔<ref>{{cite journal|vauthors=Meremikwu M, Oyo-Ita A|date=2002|title=Paracetamol for treating fever in children|journal=The Cochrane Database of Systematic Reviews|issue=2|pages=CD003676|doi=10.1002/14651858.CD003676|pmc=6532671|pmid=12076499}}</ref><ref>{{cite journal|vauthors=de Martino M, Chiarugi A|date=2015|title=Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management|journal=Pain and Therapy|volume=4|issue=2|pages=149–168|doi=10.1007/s40122-015-0040-z|pmc=4676765|pmid=26518691}}</ref> یہِ چُھچھُ اَکثَر باقٕے دَوہان سٟتؠ مِلِتھ کٕننہٕ یِوان، یِتھ کٔنہِ زن وارِیاہن سردی ہٕنٛد دَوا چھِ۔ <ref name="AHFS20162" /> پیراسیٹامول چھُ شٔدیٖد دَگہِ خٲطرٕ تہِ استعمالاِستِمال یِوان کرنہٕ، یِتھ کٔنؠ زَن کینسرٕچ دَگ تہٕ سرجری پتہٕ دَگ، اوپیئڈ دَگہِ ہٕنٛدِ دوا سٟتؠ مِلِتھ۔<ref>{{cite book|author=Scottish Intercollegiate Guidelines Network (SIGN)|title=Guideline 106: Control of pain in adults with cancer|publisher=National Health Service (NHS)|year=2008|isbn=9781905813384|location=Scotland|chapter=6.1 and 7.1.1|chapter-url=http://www.sign.ac.uk/pdf/SIGN106.pdf|archive-url=https://web.archive.org/web/20101220061154/http://sign.ac.uk/pdf/SIGN106.pdf|archive-date=20 December 2010|url-status=live|df=}}</ref> یہِ چُھچھُ عموٗمَن یا تہِ ٲسہ کِن یا ریٚکٹہِ پٲٹھہِ اِستعمال کرنہٕ یِوان، مگر یہِ چُھچھُ رَگہِ منٛزمَنٛز اِنٛجیٚکشَن ذٔریعہٕ تہِ دِنہٕ یِوان۔<ref name="AHFS20162" /><ref name="Hoch20142">{{cite book|last=Hochhauser|first=Daniel|url=https://books.google.com/books?id=CXjDBAAAQBAJ&pg=PA119|title=Cancer and its Management|date=2014|publisher=John Wiley & Sons|isbn=9781118468715|page=119|author-link=Daniel Hochhauser|archive-url=https://web.archive.org/web/20170908185107/https://books.google.com/books?id=CXjDBAAAQBAJ&pg=PA119|archive-date=8 September 2017|url-status=live}}</ref> اَمیُک اثر چُھچھُ روزان دون پؠٹھ ژورن گھنٹن درمیان۔<ref name="Hoch20142" />

پیراسیٹامول چھُ عموٗمَن تجویٖز کرنہٕ آمٕژ خوراکَن پؠٹھ محفوٗظ۔<ref name="Rus20032">{{cite journal|vauthors=Russell FM, Shann F, Curtis N, Mulholland K|date=2003|title=Evidence on the use of paracetamol in febrile children|journal=Bulletin of the World Health Organization|volume=81|issue=5|pages=367–72|issn=0042-9686|pmc=2572451|pmid=12856055|hdl=10665/268935}}</ref> أکِس بالغ سٕنٛدِ خٲطرٕ چُھچھُ تجویٖز کرنہٕ آمُت زِیٛادٕ کھۄتہٕ زِیٛادٕ دوذ ترے پؠٹھ ژور گرٛام۔<ref name="UK20172">{{Cite web|title=Paracetamol for adults: painkiller to treat aches, pains and fever|url=https://www.nhs.uk/medicines/paracetamol-for-adults/|url-status=live|archive-url=https://web.archive.org/web/20170822174155/https://beta.nhs.uk/medicines/paracetamol-for-adults|archive-date=22 August 2017|access-date=22 August 2017|website=[[National Health Service]]}}</ref><ref name="Med20182">{{cite web|title=What are the recommended maximum daily dosages of acetaminophen in adults and children?|url=https://www.medscape.com/answers/820200-27207/what-are-the-recommended-maximum-daily-dosages-of-acetaminophen-in-adults-and-children|url-status=live|archive-url=https://web.archive.org/web/20181221041534/https://www.medscape.com/answers/820200-27207/what-are-the-recommended-maximum-daily-dosages-of-acetaminophen-in-adults-and-children|archive-date=21 December 2018|access-date=19 December 2018|website=Medscape}}</ref><ref name="BMJ20152">{{cite journal|vauthors=Machado GC, Maher CG, Ferreira PH, Pinheiro MB, Lin CW, Day RO, McLachlan AJ, Ferreira ML|date=31 March 2015|title=Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials.|journal=BMJ (Clinical Research Ed.)|volume=350|pages=h1225|doi=10.1136/bmj.h1225|pmc=4381278|pmid=25828856}}</ref> زیادٕزیٛادٕ خۄراک ہیٚکہٕ زہریلہٕ ہنٛد بٲعث بنتھ،یَتھ مَنٛز جگر ناکام گژھَن شٲمِل چھُ۔<ref name="AHFS20162" /> مٕسلٕچ دَگ یۄس واریاہ شٔدیٖد چھِ تِم ہیٚکن کُنہِ ساتہٕ گٔژھِتھ، مگر یہِ چُھچھُ نایاب آسان۔<ref name="AHFS20162" /> یہِ چُھچھُ باسان حملس دوران تہٕ ماجہِ ہُنٛد دۄد دِنہٕ وِزِ محفوٗظ۔<ref name="AHFS20162" /> جگرٕچ بؠٲرؠ والیٚن منٛزمَنٛز ہیٚکو یہِ استعمالاِستِمال کٔرِتھ، مگر کم خوراکن منٛز۔مَنٛز۔<ref>{{cite journal|vauthors=Lewis JH, Stine JG|date=June 2013|title=Review article: prescribing medications in patients with cirrhosis - a practical guide|journal=Alimentary Pharmacology & Therapeutics|volume=37|issue=12|pages=1132–56|doi=10.1111/apt.12324|pmid=23638982}}</ref> اَتھ ہلکہٕ اینالجیسک پٲٹھؠ درجہٕ بندی کرنہٕ آمٔژ۔<ref name="Hoch20142" /> اَتھ منٛزمَنٛز چھَنہٕ ورمس خٕلاف زیادٕزیٛادٕ سرگرمی۔<ref name="McK20132">{{cite book|last1=McKay|first1=Gerard A.|title=Lecture Notes Clinical Pharmacology and Therapeutics|last2=Walters|first2=Matthew R.|date=2013|publisher=Wiley|isbn=9781118344897|edition=9th|location=Hoboken|chapter=Non-Opioid Analgesics|access-date=5 August 2020|chapter-url=https://books.google.com/books?id=OGOqcfN_Cc8C&pg=PT353|archive-url=https://web.archive.org/web/20170908185108/https://books.google.com/books?id=OGOqcfN_Cc8C&pg=PT353|archive-date=8 September 2017|url-status=live}}</ref> یہٕ کِتھ کٔنؠ چُھچھُ کٲم کران یہٕ چُھنہٕ مکمل طورس پیٹھپؠٹھ واضح۔<ref name="McK20132" /><ref name="Ghanem20162">{{cite journal|vauthors=Ghanem CI, Pérez MJ, Manautou JE, Mottino AD|date=July 2016|title=Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.|journal=Pharmacological Research|volume=109|pages=119–31|doi=10.1016/j.phrs.2016.02.020|pmc=4912877|pmid=26921661}}</ref><ref name="pmid183814602">{{cite journal|vauthors=Viswanathan AN, Feskanich D, Schernhammer ES, Hankinson SE|year=2008|title=Aspirin, NSAID, and Acetaminophen Use and the Risk of Endometrial Cancer|journal=Cancer Research|volume=68|issue=7|pages=2507–2513|doi=10.1158/0008-5472.CAN-07-6257|pmc=2857531|pmid=18381460}}</ref>

پیراسیٹامول آو گۄڈٕنِچہِ لَٹہِ 1877 منٛزمَنٛز بناونہٕ ۔<ref>{{cite book|last1=Mangus|first1=Brent C.|url=https://books.google.com/books?id=tV72AAAAQBAJ&pg=PA39|title=Pharmacology application in athletic training|last2=Miller|first2=Michael G.|date=2005|publisher=F.A. Davis|isbn=9780803620278|location=Philadelphia, Pennsylvania|page=39|access-date=5 August 2020|archive-url=https://web.archive.org/web/20170908185108/https://books.google.com/books?id=tV72AAAAQBAJ&pg=PA39|archive-date=8 September 2017|url-status=live}}</ref> یہِ چھُ [[اَمریٖکہ|امریکہ]] تہٕ [[یوٗرَپ|یورپ]] دۄشوٕنی منٛزمَنٛز دَگ تہٕ تپھ خٲطرٕ سارِوٕے کھۄتہٕ زِیٛادٕ استعمالاِستِمال گژھَن وول دوا ۔<ref>{{cite book|last=Aghababian|first=Richard V.|url=https://books.google.com/books?id=HnbKaRQAXOIC&pg=PA814|title=Essentials of emergency medicine|date=22 October 2010|publisher=Jones & Bartlett Publishers|isbn=978-1-4496-1846-9|page=814|archive-url=https://web.archive.org/web/20160817202827/https://books.google.com/books?id=HnbKaRQAXOIC&pg=PA814|archive-date=17 August 2016|url-status=live}}</ref> یہِ چھُ ورلڈ ہیلتھ آرگنائزیشن کِس ضروٗری ادوِیاتن ہِنٛدِس فہرستَس منٛزمَنٛز شٲمِل۔<ref name="WHO21st2">{{cite book|title=World Health Organization model list of essential medicines: 21st list 2019|vauthors=((World Health Organization))|publisher=World Health Organization|year=2019|location=Geneva|hdl=10665/325771|id=WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO|author-link=World Health Organization|hdl-access=free}}</ref> پیراسیٹامول چھُ اکھاَکھ عام دواہ پٲٹھؠ دٔستِیاب، یَتھ منٛزمَنٛز برانڈٕک ناو چھِ یِمَن منٛزمَنٛز ٹایلینول تہٕ پاناڈول تہِ شٲمِل چھِ۔<ref>{{cite book|last1=Hamilton|first1=Richard J.|url=https://books.google.com/books?id=lwueJ4IAl4oC&pg=PA12|title=Tarascon pocket pharmacopoeia : 2013 classic shirt-pocket edition|date=2013|publisher=Jones & Bartlett Learning|isbn=9781449665869|edition=27th|location=Burlington, Massachusetts|page=12|archive-url=https://web.archive.org/web/20170908185107/https://books.google.com/books?id=lwueJ4IAl4oC&pg=PA12|archive-date=8 September 2017|url-status=live}}</ref> 2017 ہَس منٛزمَنٛز اوس یہِ امریکہَس منٛزمَنٛز 25 ہِم سارِوٕے کھۄتہٕ زِیٛادٕ تجویٖز کرنہٕ آمُت دوا یَتھ منٛزمَنٛز 24 ملین کھۄتہٕ زِیٛادٕ نسخہٕ ٲسؠ۔<ref>{{cite web|title=The Top 300 of 2020|url=https://clincalc.com/DrugStats/Top300Drugs.aspx|url-status=live|archive-url=https://web.archive.org/web/20210212142534/https://clincalc.com/DrugStats/Top300Drugs.aspx|archive-date=12 February 2021|access-date=25 February 2020|publisher=ClinCalc}}</ref><ref>{{cite web|title=Acetaminophen Drug Usage Statistics|url=https://clincalc.com/DrugStats/Drugs/Acetaminophen|url-status=live|archive-url=https://web.archive.org/web/20200412005634/https://clincalc.com/DrugStats/Drugs/Acetaminophen|archive-date=12 April 2020|access-date=11 April 2020|website=ClinCalc}}</ref>

== حوالہٕحَوالہٕ ==